Across TCGA pan-cancer cohorts, CEACAM18 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CEACAM18’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CEACAM18 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CEACAM18 is over-expressed in tumor, although a few such as PRAD show the opposite, repressed pattern.

HNSC, PAAD, and PRAD are the cancer types where CEACAM18 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CEACAM18 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.016	.021	3	view →
PAAD	Female	All	+1.660	.049	2	view →
PRAD	All	All	−0.005	.048	2	view →
KIRC	All	All	+0.005	.011	2	view →
COAD	All	All	+0.420	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: CEACAM18 RNA expression & survival · all CEACAM18 data types