Across TCGA cell cohorts, CEACAM18 mutation is significantly associated with the mutation status of many other genes, with 1,938 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEACAM18-associated genes across cancer lineages are SLC18A1, CNGA3, and IKZF1. Each is linked with CEACAM18 in more than 3 cancer types. Because this analysis shows association rather than direction, both CEACAM18-to-partner and partner-to-CEACAM18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM18→partner) and Y-score (partner→CEACAM18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SLC18A1 →	+3.548	+2.830	.009	.009	1	4
LARGE_INTESTINE	CNGA3 →	+1.959	+1.959	.009	.009	1	4
LARGE_INTESTINE	IKZF1 →	+1.989	+2.148	.003	.003	1	4
SKIN	SYT16 →	+4.548	+3.906	<.001	<.001	1	3
SKIN	PLA2R1 →	+2.641	+2.548	.008	.008	1	3
SKIN	ZSCAN12 →	+4.548	+3.169	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,938 associations by consensus.

Exploration

CEACAM18 survival (RNA) · tumor vs normal (RNA) · all CEACAM18 data types