CEACAM1

Across TCGA pan-cancer cohorts, CEACAM1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CEACAM1 data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CEACAM1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CEACAM1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and UCEC show a favorable association.

CCRCC, PDAC, and UCEC are the cancer types where CEACAM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	1.000	0.841	.010	16	view →
PDAC	DFS	Tertile	II,III,IV	0.263	0.454	.006	13	view →
UCEC	OS	Median	All	0.982	0.915	.039	12	view →
GBM	DFS	Median	All	0.655	0.801	.027	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CEACAM1–CCRCC (OS)

Open the CCRCC breakdown →