CEACAM1

Across TCGA cell cohorts, CEACAM1 mutation is significantly associated with the RNA expression of many other genes, with 219 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CEACAM1-associated genes across cancer lineages are OR4X2, TRABD, and MROH5. Each is linked with CEACAM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEACAM1-to-partner and partner-to-CEACAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4X2 grouped by CEACAM1-low versus CEACAM1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM1→partner) and Y-score (partner→CEACAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR4X2 →	+0.018	+5.369	.001	.004	3	2
LUNG_NSCLC_LUAD	TRABD →	+0.443	+2.459	.008	.008	3	2
SOFT_TISSUE	MROH5 →	+0.021	+4.930	<.001	.008	3	1
SOFT_TISSUE	LCE6A →	+0.040	+5.977	<.001	.001	3	1
SOFT_TISSUE	UBTFL1 →	+0.043	+5.369	<.001	.004	3	1
SOFT_TISSUE	PRAMEF18 →	+0.026	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 219 associations by consensus.

OR4X2 by CEACAM1 expression — SOFT_TISSUE

Explore this box plot interactively →