CDX4

Across TCGA patient cohorts, CDX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,388 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CDX4-associated GO terms across cancer lineages are Peroxisome fission, Obsolete ubiquitin-dependent ERAD pathway, and Mammary gland epithelial cell proliferation. Each is linked with CDX4 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDX4-to-partner and partner-to-CDX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peroxisome fission grouped by CDX4-low versus CDX4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDX4→partner) and Y-score (partner→CDX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Peroxisome fission →	+0.038	+0.028	<.001	.001	3	6
STAD	Obsolete ubiquitin-dependent ERAD pathway →	+0.072	+0.036	<.001	<.001	3	6
STAD	Mammary gland epithelial cell proliferation →	+0.071	+0.034	<.001	<.001	3	6
STAD	ERAD pathway →	+0.069	+0.037	<.001	<.001	3	6
STAD	Regulation of generation of precursor metabolites and energy →	+0.063	+0.035	<.001	<.001	3	6
STAD	Regulation of epidermis development →	+0.061	+0.042	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,388 associations by consensus.

Peroxisome fission by CDX4 expression — STAD

Explore this box plot interactively →