CDX4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CDX4 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDX4-associated genes across cancer lineages are LCE1C. Each is linked with CDX4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDX4-to-partner and partner-to-CDX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE1C grouped by CDX4-low versus CDX4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDX4→partner) and Y-score (partner→CDX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINELCE1C →+0.062+3.684.004.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

LCE1C by CDX4 expression — LARGE_INTESTINE

Box plot of LCE1C in CDX4-low vs CDX4-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration