CDT1

Across TCGA patient cohorts, CDT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,342 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDT1-associated proteins across cancer lineages are RRM1, RRM2, and SMC2. Each is linked with CDT1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CDT1-to-partner and partner-to-CDT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDT1 versus RRM1 in GBM, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDT1→partner) and Y-score (partner→CDT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RRM1 →	+0.427	+0.644	<.001	<.001	3	10
LUAD	RRM2 →	+0.867	+1.147	<.001	<.001	3	10
GBM	SMC2 →	+0.708	+0.836	<.001	<.001	3	10
OV	SMC4 →	+0.694	+1.281	<.001	<.001	3	10
LUAD	CDC20_T70 →	+1.211	+1.211	<.001	<.001	3	10
LUAD	CDK1 →	+0.790	+1.086	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,342 associations by consensus.

CDT1 vs RRM1 — GBM

Explore this scatter interactively →