CDT1

Across TCGA patient cohorts, CDT1 protein abundance is significantly associated with the RNA expression of many other genes, with 551 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDT1-associated genes across cancer lineages are SYP, MDK, and EPM2A. Each is linked with CDT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDT1-to-partner and partner-to-CDT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDT1 versus SYP in UCEC, with a Pearson correlation of -0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDT1→partner) and Y-score (partner→CDT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SYP →	-0.426	-1.390	<.001	.005	3	1
UCEC	MDK →	+1.425	+1.373	.002	.005	3	1
UCEC	EPM2A →	-0.399	-1.390	.008	.005	3	1
UCEC	FAM20B →	-0.410	-1.373	.007	.005	3	1
UCEC	SIRPD →	-0.672	-1.677	.001	.003	3	1
UCEC	SIX1 →	+2.670	+1.892	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 551 associations by consensus.

CDT1 vs SYP — UCEC

Explore this scatter interactively →