CDR2

Across TCGA patient cohorts, CDR2 mutation is significantly associated with the RNA expression of many other genes, with 1,652 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDR2-associated genes across cancer lineages are RNU6-1106P, MIR6766, and MT-TN. Each is linked with CDR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDR2-to-partner and partner-to-CDR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1106P grouped by CDR2-low versus CDR2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDR2→partner) and Y-score (partner→CDR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1106P →	+0.209	+5.212	<.001	.002	3	3
BLCA	MIR6766 →	+0.613	+6.018	<.001	.002	3	2
HNSC	MT-TN →	+0.369	+4.822	<.001	.006	3	2
COAD	RN7SL656P →	+0.148	+4.595	<.001	.004	3	2
HNSC	CBX3P8 →	+0.066	+5.221	<.001	.003	3	2
UCEC	PLCH1-AS2 →	+0.179	+2.006	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,652 associations by consensus.

RNU6-1106P by CDR2 expression — SKCM

Explore this box plot interactively →