CDO1

Across TCGA patient cohorts, CDO1 mutation is significantly associated with the RNA expression of many other genes, with 2,942 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDO1-associated genes across cancer lineages are MIR615, FAM177A1, and SLC25A4. Each is linked with CDO1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDO1-to-partner and partner-to-CDO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR615 grouped by CDO1-low versus CDO1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDO1→partner) and Y-score (partner→CDO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR615 →	+0.800	+5.411	<.001	.005	3	3
UCEC	FAM177A1 →	+0.370	+3.016	<.001	<.001	3	2
UCEC	SLC25A4 →	+0.402	+2.010	.006	.005	3	2
UCEC	DPEP1 →	-0.929	-1.991	.009	.009	3	2
UCEC	SKA1 →	+0.805	+2.595	<.001	<.001	3	2
UCEC	PEF1 →	+0.268	+2.971	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,942 associations by consensus.

MIR615 by CDO1 expression — BLCA

Explore this box plot interactively →