CDO1

Across TCGA cell cohorts, CDO1 mutation is significantly associated with the mutation status of many other genes, with 575 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDO1-associated genes across cancer lineages are NKG7, SIPA1L3, and CHN2. Each is linked with CDO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDO1-to-partner and partner-to-CDO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NKG7 grouped by CDO1-low versus CDO1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDO1→partner) and Y-score (partner→CDO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	NKG7 →	+5.339	+4.772	.004	.004	1	2
LUNG_NSCLC_LUAD	SIPA1L3 →	+5.339	+4.772	.004	.004	1	2
LUNG_NSCLC_LUAD	CHN2 →	+5.339	+4.772	.004	.004	1	2
LUNG_NSCLC_LUAD	PRB2 →	+4.924	+5.584	<.001	<.001	1	2
LUNG_NSCLC_LUAD	MED13L →	+4.339	+4.339	.009	.009	1	2
LUNG_NSCLC_LUAD	USP36 →	+4.339	+4.339	.009	.009	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 575 associations by consensus.

NKG7 by CDO1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →