CDKN3

Across TCGA patient cohorts, CDKN3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,353 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CDKN3-associated genes across cancer lineages are CFAP410, POLM, and EPHX2. Each is linked with CDKN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDKN3-to-partner and partner-to-CDKN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDKN3 versus CFAP410 in GBM, with a Pearson correlation of -0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN3→partner) and Y-score (partner→CDKN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CFAP410 →	-0.769	-0.763	.005	.009	3	2
GBM	POLM →	-1.236	-0.763	.003	.009	3	2
LUAD	EPHX2 →	-0.866	-3.769	.006	<.001	3	1
LUAD	SLC25A16 →	-0.690	-3.850	.006	<.001	3	1
LUAD	BARHL1 →	-0.230	-3.866	<.001	<.001	3	1
LUAD	MAP3K10 →	-0.716	-3.876	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,353 associations by consensus.

CDKN3 vs CFAP410 — GBM

Explore this scatter interactively →