CDKN2D

Across TCGA patient cohorts, CDKN2D protein abundance is significantly associated with the RNA expression of many other genes, with 3,623 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDKN2D-associated genes across cancer lineages are MDK, SELENOS, and BRS3. Each is linked with CDKN2D in more than 1 cancer types. Because this analysis shows association rather than direction, both CDKN2D-to-partner and partner-to-CDKN2D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDKN2D versus MDK in PDAC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN2D→partner) and Y-score (partner→CDKN2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MDK →	+1.303	+1.103	.009	.002	3	2
LUAD	SELENOS →	+0.424	+0.442	<.001	.001	3	2
OV	BRS3 →	+0.180	+0.530	.003	.001	3	1
OV	MEFV →	+0.451	+0.400	.001	.002	3	1
OV	HIVEP2 →	+2.150	+0.496	.004	.006	3	1
OV	KCTD10 →	+0.642	+0.356	.008	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,623 associations by consensus.

CDKN2D vs MDK — PDAC

Explore this scatter interactively →