CDKN2D

Across TCGA patient cohorts, CDKN2D mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CDKN2D-associated genes across cancer lineages are MIR489 and RNA5SP291. Each is linked with CDKN2D in more than 1 cancer types. Because this analysis shows association rather than direction, both CDKN2D-to-partner and partner-to-CDKN2D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR489 grouped by CDKN2D-low versus CDKN2D-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN2D→partner) and Y-score (partner→CDKN2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR489 →	+0.406	+7.930	<.001	.008	3	1
LUAD	RNA5SP291 →	+0.552	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MIR489 by CDKN2D expression — LUAD

Explore this box plot interactively →