CDKN2D

Across TCGA cell cohorts, CDKN2D RNA expression is significantly associated with the go_rna of many other GO terms, with 4,257 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDKN2D-associated GO terms across cancer lineages are Autophagic cell death, Amino acid metabolic process, and Regulation of glycolytic process through fructose-6-phosphate. Each is linked with CDKN2D in more than 17 cancer types. Because this analysis shows association rather than direction, both CDKN2D-to-partner and partner-to-CDKN2D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagic cell death grouped by CDKN2D-low versus CDKN2D-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN2D→partner) and Y-score (partner→CDKN2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Autophagic cell death →	+0.196	+1.622	<.001	<.001	3	18
BONE	Amino acid metabolic process →	-0.076	-1.367	<.001	<.001	3	13
BREAST	Regulation of glycolytic process through fructose-6-phosphate →	+0.175	+1.678	<.001	<.001	3	13
BREAST	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.175	+1.678	<.001	<.001	3	13
LUNG_SCLC	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.170	+1.800	<.001	<.001	3	12
LUNG_SCLC	Regulation of ubiquitin protein ligase activity →	+0.224	+1.843	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,257 associations by consensus.

Autophagic cell death by CDKN2D expression — BLOOD_Myeloma

Explore this box plot interactively →