CDKN2D

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CDKN2D mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDKN2D-associated genes across cancer lineages are GSG1L2. Each is linked with CDKN2D in more than 1 cancer types. Because this analysis shows association rather than direction, both CDKN2D-to-partner and partner-to-CDKN2D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSG1L2 grouped by CDKN2D-low versus CDKN2D-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN2D→partner) and Y-score (partner→CDKN2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEGSG1L2 →+0.016+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

GSG1L2 by CDKN2D expression — LARGE_INTESTINE

Box plot of GSG1L2 in CDKN2D-low vs CDKN2D-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration