CDKN2B

Across TCGA cell cohorts, CDKN2B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CDKN2B-associated genes across cancer lineages are OR4F5 and CASR. Each is linked with CDKN2B in more than 1 cancer types. Because this analysis shows association rather than direction, both CDKN2B-to-partner and partner-to-CDKN2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F5 grouped by CDKN2B-low versus CDKN2B-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN2B→partner) and Y-score (partner→CDKN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR4F5 →	+0.040	+4.196	<.001	.006	3	1
BREAST	CASR →	+0.013	+4.415	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR4F5 by CDKN2B expression — BREAST

Explore this box plot interactively →