CDKN2B-AS1

Across TCGA patient cohorts, CDKN2B-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,146 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible CDKN2B-AS1-associated GO terms across cancer lineages are Regulation of sister chromatid segregation, Regulation of cyclin-dependent protein kinase activity, and Regulation of mitotic sister chromatid segregation. Each is linked with CDKN2B-AS1 in more than 23 cancer types. Because this analysis shows association rather than direction, both CDKN2B-AS1-to-partner and partner-to-CDKN2B-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of sister chromatid segregation grouped by CDKN2B-AS1-low versus CDKN2B-AS1-high in ACC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN2B-AS1→partner) and Y-score (partner→CDKN2B-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	Regulation of sister chromatid segregation →	+0.083	+0.658	<.001	<.001	3	24
STAD	Regulation of cyclin-dependent protein kinase activity →	+0.042	+0.394	<.001	<.001	3	23
THYM	Regulation of mitotic sister chromatid segregation →	+0.075	+0.368	<.001	<.001	3	23
ACC	Mitotic nuclear division →	+0.071	+0.616	<.001	<.001	3	23
ACC	Negative regulation of mitotic cell cycle →	+0.053	+0.632	<.001	<.001	3	23
ACC	Chromosome separation →	+0.108	+0.613	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,146 associations by consensus.

Regulation of sister chromatid segregation by CDKN2B-AS1 expression — ACC

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