CDKN1C

Across TCGA cell cohorts, CDKN1C RNA expression is significantly associated with the go_rna of many other GO terms, with 2,668 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CDKN1C-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Cytoplasmic translation. Each is linked with CDKN1C in more than 9 cancer types. Because this analysis shows association rather than direction, both CDKN1C-to-partner and partner-to-CDKN1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by CDKN1C-low versus CDKN1C-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN1C→partner) and Y-score (partner→CDKN1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.112	+2.099	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.075	+1.448	<.001	.004	3	10
URINARY_TRACT	Cytoplasmic translation →	+0.078	+1.478	.002	.002	3	10
UPPER_AERODIGESTIVE_TRACT	Mitochondrial electron transport, cytochrome c to oxygen →	+0.093	+1.355	<.001	.001	3	10
CNS	COPII-coated vesicle budding →	+0.080	+1.300	<.001	<.001	3	9
OVARY	Regulation of myoblast fusion →	+0.112	+2.215	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,668 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by CDKN1C expression — OVARY

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