CDKN1B

Across TCGA patient cohorts, CDKN1B protein abundance is significantly associated with the RNA expression of many other genes, with 14,480 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDKN1B-associated genes across cancer lineages are TRIP13, BUB1, and KPNA2. Each is linked with CDKN1B in more than 8 cancer types. Because this analysis shows association rather than direction, both CDKN1B-to-partner and partner-to-CDKN1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDKN1B versus TRIP13 in LUAD, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN1B→partner) and Y-score (partner→CDKN1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TRIP13 →	-0.861	-0.275	.003	<.001	3	9
OV	BUB1 →	-1.055	-0.502	<.001	<.001	3	8
HNSC	KPNA2 →	-0.811	-0.407	<.001	.001	3	8
OV	CBX7 →	+0.730	+0.456	<.001	.002	3	7
OV	CEP55 →	-1.168	-0.405	<.001	.008	2	8
OV	CDCA5 →	-1.054	-0.467	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,480 associations by consensus.

CDKN1B vs TRIP13 — LUAD

Explore this scatter interactively →