CDKN1B

Across TCGA cell cohorts, CDKN1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,099 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CDKN1B-associated GO terms across cancer lineages are Cellular response to lithium ion, Response to lithium ion, and Regulation of double-strand break repair. Each is linked with CDKN1B in more than 14 cancer types. Because this analysis shows association rather than direction, both CDKN1B-to-partner and partner-to-CDKN1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to lithium ion grouped by CDKN1B-low versus CDKN1B-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN1B→partner) and Y-score (partner→CDKN1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Cellular response to lithium ion →	+0.216	+1.331	.002	.003	3	15
BREAST	Response to lithium ion →	+0.176	+1.347	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair →	+0.070	+0.969	.002	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of double-strand break repair →	+0.079	+1.100	.003	.001	3	9
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.119	+1.181	<.001	<.001	3	9
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.051	+0.888	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,099 associations by consensus.

Cellular response to lithium ion by CDKN1B expression — BLOOD_Myeloma

Explore this box plot interactively →