CDKN1A

Across TCGA patient cohorts, CDKN1A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,996 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDKN1A-associated proteins across cancer lineages are PARP1, MAP7D1_S70, and RBM39. Each is linked with CDKN1A in more than 7 cancer types. Because this analysis shows association rather than direction, both CDKN1A-to-partner and partner-to-CDKN1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDKN1A versus PARP1 in HNSC, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN1A→partner) and Y-score (partner→CDKN1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PARP1 →	-0.631	-0.951	<.001	.001	2	8
HNSC	MAP7D1_S70 →	+1.076	+0.991	<.001	.001	3	7
GBM	RBM39 →	-0.309	-0.959	<.001	<.001	3	6
OV	SART3 →	-0.325	-1.116	<.001	<.001	3	6
HNSC	MYO1E →	+0.381	+0.902	<.001	<.001	3	6
HNSC	TNKS1BP1_S1073 →	+0.630	+0.714	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,996 associations by consensus.

CDKN1A vs PARP1 — HNSC

Explore this scatter interactively →