Across TCGA patient cohorts, CDKL4 RNA expression is significantly associated with the RNA expression of many other genes, with 15,461 significant associations in total. UVM shows the largest number of these associations.

The most reproducible CDKL4-associated genes across cancer lineages are CEP95, HERC2P9, and FAM228B. Each is linked with CDKL4 in more than 21 cancer types. Because this analysis shows association rather than direction, both CDKL4-to-partner and partner-to-CDKL4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKL4→partner) and Y-score (partner→CDKL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	CEP95 →	+1.021	+0.133	<.001	<.001	3	22
UVM	HERC2P9 →	+0.885	+0.153	<.001	<.001	3	21
UVM	FAM228B →	+0.789	+0.130	<.001	.004	3	21
UVM	SUZ12P1 →	+0.938	+0.150	<.001	<.001	3	21
UVM	DMTF1 →	+1.287	+0.126	<.001	<.001	3	21
UVM	USP45 →	+0.735	+0.141	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,461 associations by consensus.

Exploration

CDKL4 survival (RNA) · tumor vs normal (RNA) · all CDKL4 data types