CDK9

Across TCGA patient cohorts, CDK9 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,135 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CDK9-associated proteins across cancer lineages are HSP90B1, FUBP3, and PDIA6. Each is linked with CDK9 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDK9-to-partner and partner-to-CDK9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK9 versus HSP90B1 in LUAD, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK9→partner) and Y-score (partner→CDK9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HSP90B1 →	-0.384	-0.329	<.001	<.001	3	6
LSCC	FUBP3 →	+0.179	+0.321	<.001	<.001	3	6
LUAD	PDIA6 →	-0.332	-0.331	<.001	<.001	3	5
OV	PTPA →	+0.454	+0.459	.002	.003	3	5
LUAD	PDIA4 →	-0.453	-0.340	<.001	<.001	3	5
COAD	EHMT1 →	+0.369	+0.491	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,135 associations by consensus.

CDK9 vs HSP90B1 — LUAD

Explore this scatter interactively →