CDK9

Across TCGA patient cohorts, CDK9 protein abundance is significantly associated with the RNA expression of many other genes, with 17,219 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDK9-associated genes across cancer lineages are TIMELESS, CCNT1, and SENP1. Each is linked with CDK9 in more than 7 cancer types. Because this analysis shows association rather than direction, both CDK9-to-partner and partner-to-CDK9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK9 versus TIMELESS in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK9→partner) and Y-score (partner→CDK9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIMELESS →	+0.958	+0.202	<.001	.001	3	8
LSCC	CCNT1 →	+0.651	+0.353	<.001	<.001	3	7
LSCC	SENP1 →	+0.591	+0.290	<.001	<.001	3	7
LSCC	RFC5 →	+0.831	+0.304	<.001	<.001	3	6
HNSC	COPZ1 →	+0.421	+0.285	.001	<.001	3	6
LSCC	CDK2 →	+0.655	+0.274	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,219 associations by consensus.

CDK9 vs TIMELESS — UCEC

Explore this scatter interactively →