CDK5RAP3

Across TCGA patient cohorts, CDK5RAP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,829 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDK5RAP3-associated proteins across cancer lineages are PRPF6, NUP205, and LIG3. Each is linked with CDK5RAP3 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDK5RAP3-to-partner and partner-to-CDK5RAP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK5RAP3 versus PRPF6 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK5RAP3→partner) and Y-score (partner→CDK5RAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PRPF6 →	+0.353	+0.496	<.001	<.001	3	7
GBM	NUP205 →	+0.185	+0.333	.003	.004	3	6
GBM	LIG3 →	+0.374	+0.448	<.001	<.001	3	6
GBM	ZC3H13_T362 →	+0.362	+0.350	<.001	.001	3	6
GBM	SF3B3 →	+0.252	+0.423	<.001	<.001	3	6
PDAC	EFTUD2 →	+0.213	+0.369	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,829 associations by consensus.

CDK5RAP3 vs PRPF6 — LSCC

Explore this scatter interactively →