CDK5RAP2

Across TCGA patient cohorts, CDK5RAP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,186 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDK5RAP2-associated proteins across cancer lineages are BRD3, ANP32B, and WDR5. Each is linked with CDK5RAP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDK5RAP2-to-partner and partner-to-CDK5RAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK5RAP2 versus BRD3 in GBM, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK5RAP2→partner) and Y-score (partner→CDK5RAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BRD3 →	+0.395	+0.481	<.001	<.001	3	7
GBM	ANP32B →	+0.482	+0.454	<.001	<.001	3	7
GBM	WDR5 →	+0.327	+0.431	<.001	<.001	3	6
LSCC	FUBP3 →	+0.199	+0.695	<.001	<.001	3	6
BRCA	RAD23B →	+0.245	+0.509	.002	.004	3	6
GBM	HNRNPK →	+0.266	+0.323	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,186 associations by consensus.

CDK5RAP2 vs BRD3 — GBM

Explore this scatter interactively →