CDK5RAP2

Across TCGA cell cohorts, CDK5RAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,891 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDK5RAP2-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, DNA-templated DNA replication maintenance of fidelity, and DNA biosynthetic process. Each is linked with CDK5RAP2 in more than 17 cancer types. Because this analysis shows association rather than direction, both CDK5RAP2-to-partner and partner-to-CDK5RAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by CDK5RAP2-low versus CDK5RAP2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK5RAP2→partner) and Y-score (partner→CDK5RAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	DNA strand elongation involved in DNA replication →	+0.162	+1.108	.001	<.001	3	18
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.103	+0.735	.006	.005	3	18
UPPER_AERODIGESTIVE_TRACT	DNA biosynthetic process →	+0.079	+0.761	.001	.002	3	17
BONE	Centriole assembly →	+0.097	+0.739	.006	.007	3	17
LARGE_INTESTINE	Regulation of chromosome condensation →	+0.184	+0.727	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.113	+0.815	.002	.002	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,891 associations by consensus.

DNA strand elongation involved in DNA replication by CDK5RAP2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →