CDK18

Across TCGA patient cohorts, CDK18 RNA expression is significantly associated with the RNA expression of many other genes, with 17,762 significant associations in total. ACC shows the largest number of these associations.

The most reproducible CDK18-associated genes across cancer lineages are ZNF687, PYCR2, and ZFP41. Each is linked with CDK18 in more than 25 cancer types. Because this analysis shows association rather than direction, both CDK18-to-partner and partner-to-CDK18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK18 versus ZNF687 in ACC, with a Pearson correlation of 0.51.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK18→partner) and Y-score (partner→CDK18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	ZNF687 →	+0.972	+1.296	<.001	<.001	3	26
ACC	PYCR2 →	+1.143	+1.277	<.001	<.001	3	26
SCLC	ZFP41 →	+0.826	+0.825	<.001	<.001	3	26
TGCT	IQSEC2 →	+0.848	+0.596	<.001	<.001	3	26
UCS	TMEM63A →	+1.419	+1.538	<.001	<.001	3	26
THYM	ARHGEF11 →	+1.485	+0.877	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,762 associations by consensus.

CDK18 vs ZNF687 — ACC

Explore this scatter interactively →