CDK16

Across TCGA patient cohorts, CDK16 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,847 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDK16-associated proteins across cancer lineages are HMGB3, MCM7, and ECT2_T359. Each is linked with CDK16 in more than 7 cancer types. Because this analysis shows association rather than direction, both CDK16-to-partner and partner-to-CDK16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK16 versus HMGB3 in LUAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK16→partner) and Y-score (partner→CDK16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HMGB3 →	+0.905	+0.505	<.001	<.001	3	8
GBM	MCM7 →	+0.647	+0.577	.001	<.001	3	8
PDAC	ECT2_T359 →	+0.987	+0.435	<.001	<.001	3	7
GBM	KIF11 →	+0.696	+0.516	<.001	<.001	3	7
LSCC	MCM2 →	+0.610	+0.626	<.001	<.001	3	7
GBM	MCM3 →	+0.628	+0.467	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,847 associations by consensus.

CDK16 vs HMGB3 — LUAD

Explore this scatter interactively →