CDK11B

Across TCGA patient cohorts, CDK11B mutation is significantly associated with the RNA expression of many other genes, with 863 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDK11B-associated genes across cancer lineages are RN7SL415P, LINC02123, and RNA5SP110. Each is linked with CDK11B in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK11B-to-partner and partner-to-CDK11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL415P grouped by CDK11B-low versus CDK11B-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK11B→partner) and Y-score (partner→CDK11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL415P →	+0.151	+4.812	<.001	.006	3	2
CESC	LINC02123 →	+0.031	+6.164	<.001	<.001	3	2
CESC	RNA5SP110 →	+0.217	+6.164	<.001	<.001	3	2
CESC	LINC00489 →	+0.079	+6.584	<.001	<.001	3	2
SKCM	RPS3AP9 →	+0.056	+3.099	.001	.007	3	2
COAD	OR4A21P →	+0.116	+5.142	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 863 associations by consensus.

RN7SL415P by CDK11B expression — CESC

Explore this box plot interactively →