Across TCGA cell cohorts, CDHR4 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDHR4-associated genes across cancer lineages are ODF1, C6orf118, and GJD2. Each is linked with CDHR4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDHR4-to-partner and partner-to-CDHR4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDHR4→partner) and Y-score (partner→CDHR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ODF1 →	+0.020	+5.022	<.001	.002	3	1
LARGE_INTESTINE	C6orf118 →	+0.130	+3.115	<.001	.004	3	1
LARGE_INTESTINE	GJD2 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR1D2 →	+0.010	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TBC1D3 →	+0.076	+3.103	<.001	.004	3	1
BLOOD_Leukemia	MMP27 →	+0.015	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

CDHR4 survival (RNA) · tumor vs normal (RNA) · all CDHR4 data types