CDHR3

Across TCGA patient cohorts, CDHR3 mutation is significantly associated with the RNA expression of many other genes, with 5,181 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDHR3-associated genes across cancer lineages are COX15, MIR4797, and PHF5A. Each is linked with CDHR3 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDHR3-to-partner and partner-to-CDHR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX15 grouped by CDHR3-low versus CDHR3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDHR3→partner) and Y-score (partner→CDHR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COX15 →	+0.408	+1.947	<.001	<.001	3	4
READ	MIR4797 →	+0.819	+5.054	<.001	.001	3	3
UCEC	PHF5A →	+0.676	+3.369	<.001	<.001	3	3
UCEC	PSMA6 →	+0.456	+3.400	.002	<.001	3	3
COAD	VAPA →	+0.498	+2.598	.001	.006	3	3
UCEC	KCTD9 →	+0.858	+2.917	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,181 associations by consensus.

COX15 by CDHR3 expression — UCEC

Explore this box plot interactively →