CDHR3

Across TCGA cell cohorts, CDHR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,531 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CDHR3-associated GO terms across cancer lineages are Subtelomeric heterochromatin formation, Regulation of centriole-centriole cohesion, and Microtubule polymerization or depolymerization. Each is linked with CDHR3 in more than 8 cancer types. Because this analysis shows association rather than direction, both CDHR3-to-partner and partner-to-CDHR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Subtelomeric heterochromatin formation grouped by CDHR3-low versus CDHR3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDHR3→partner) and Y-score (partner→CDHR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Subtelomeric heterochromatin formation →	+0.108	+1.048	<.001	.001	3	9
BREAST	Regulation of centriole-centriole cohesion →	+0.118	+0.965	<.001	.001	3	8
LUNG_NSCLC_LUSC	Microtubule polymerization or depolymerization →	+0.112	+0.951	.002	<.001	3	8
STOMACH	Pre-mRNA catabolic process →	+0.121	+1.022	<.001	.005	3	8
PANCREAS	Peptidyl-lysine monomethylation →	-0.130	-1.043	<.001	<.001	3	8
OVARY	Mitochondrial DNA metabolic process →	+0.128	+0.878	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,531 associations by consensus.

Subtelomeric heterochromatin formation by CDHR3 expression — BONE

Explore this box plot interactively →