CDHR3

Across TCGA cell cohorts, CDHR3 mutation is significantly associated with the RNA expression of many other genes, with 1,061 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDHR3-associated genes across cancer lineages are RIPPLY2, OR2D3, and CLC. Each is linked with CDHR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDHR3-to-partner and partner-to-CDHR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RIPPLY2 grouped by CDHR3-low versus CDHR3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDHR3→partner) and Y-score (partner→CDHR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RIPPLY2 →	+0.251	+1.974	.003	.008	3	2
SOFT_TISSUE	OR2D3 →	+0.018	+4.930	.007	.008	3	1
LUNG_NSCLC_LUSC	CLC →	+0.094	+3.807	<.001	.003	3	1
BLOOD_Leukemia	OR11H1 →	+0.063	+4.786	<.001	<.001	3	1
BLOOD_Leukemia	SLCO1C1 →	+0.076	+3.705	<.001	.007	3	1
BLOOD_Leukemia	SHCBP1L →	+0.029	+3.551	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,061 associations by consensus.

RIPPLY2 by CDHR3 expression — LARGE_INTESTINE

Explore this box plot interactively →