CDH9

Across TCGA patient cohorts, CDH9 mutation is significantly associated with the RNA expression of many other genes, with 4,833 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDH9-associated genes across cancer lineages are C1QBP, S100B, and BOLA3. Each is linked with CDH9 in more than 4 cancer types. Because this analysis shows association rather than direction, both CDH9-to-partner and partner-to-CDH9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1QBP grouped by CDH9-low versus CDH9-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH9→partner) and Y-score (partner→CDH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C1QBP →	+0.494	+2.128	<.001	.009	3	5
HNSC	S100B →	-0.744	-3.146	.008	<.001	3	5
LUAD	BOLA3 →	+0.341	+1.674	<.001	.006	3	5
UCEC	TMEM154 →	-0.334	-1.659	.004	<.001	3	5
UCEC	ALKBH7 →	+0.368	+1.874	.001	<.001	3	5
LUAD	EEF1AKMT2 →	+0.231	+1.476	.002	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,833 associations by consensus.

C1QBP by CDH9 expression — COAD

Explore this box plot interactively →