CDH9

Across TCGA pan-cancer cohorts, CDH9 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated CDH9 data layer compared with 11 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher CDH9 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CDH9 expression acts as an unfavorable survival marker, although some lineages such as KIRP and LGG show a favorable association.

KIRP, COAD, and BLCA are the cancer types where CDH9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	II,III,IV	1.000	0.224	<.001	88	view →
COAD	DFS	Tertile	II,III,IV	0.437	0.734	<.001	84	view →
BLCA	DFS	Quartile	II,III,IV	0.455	0.660	<.001	70	view →
SKCM	OS	Tertile	All	0.091	0.418	<.001	57	view →
UVM	OS	Tertile	All	0.293	0.823	<.001	45	view →
LGG	DFS	Tertile	All	0.529	0.360	<.001	34	view →
KICH	OS	Tertile	II,III,IV	0.155	0.880	<.001	28	view →
TGCT	DFS	Median	All	0.520	0.818	.002	26	view →
LIHC	DFS	Quartile	II,III,IV	0.289	0.534	.012	22	view →
KIRC	DFS	Quartile	All	0.959	0.850	<.001	18	view →
SCLC	DFS	Median	All	0.311	0.843	.001	18	view →
HNSC	DFS	Tertile	All	0.736	0.506	.027	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

CDH9–KIRP (DFS)

Open the KIRP breakdown →