CDH9

Across TCGA patient cohorts, CDH9 mutation is significantly associated with the total protein of many other genes, with 80 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDH9-associated genes across cancer lineages are p38-MAPK_pT180_Y182, FoxM1, and Cyclin-B1. Each is linked with CDH9 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDH9-to-partner and partner-to-CDH9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p38-MAPK_pT180_Y182 grouped by CDH9-low versus CDH9-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH9→partner) and Y-score (partner→CDH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	p38-MAPK_pT180_Y182 →	-0.395	-3.149	.008	.017	3	6
UCEC	FoxM1 →	+0.190	+1.530	.015	.004	3	5
UCEC	Cyclin-B1 →	+0.644	+2.247	<.001	.001	3	4
COAD	ASNS →	+0.449	+2.459	<.001	.017	3	3
STAD	GSK-3_pS9 →	-0.437	-2.700	.004	.005	3	3
STAD	NF-kB-p65_pS536 →	-0.442	-2.000	.014	.030	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 80 associations by consensus.

p38-MAPK_pT180_Y182 by CDH9 expression — STAD

Explore this box plot interactively →