CDH9

Across TCGA cell cohorts, CDH9 mutation is significantly associated with the RNA expression of many other genes, with 284 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDH9-associated genes across cancer lineages are OR51Q1, PROP1, and ARMS2. Each is linked with CDH9 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDH9-to-partner and partner-to-CDH9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51Q1 grouped by CDH9-low versus CDH9-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH9→partner) and Y-score (partner→CDH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR51Q1 →	+0.078	+2.352	.001	.002	3	3
LIVER	PROP1 →	+0.017	+4.459	<.001	.001	3	2
LARGE_INTESTINE	ARMS2 →	+0.098	+2.160	.002	.002	3	2
LARGE_INTESTINE	UST →	+1.057	+3.169	.007	.009	3	2
LARGE_INTESTINE	GRK7 →	+0.091	+2.441	<.001	.001	3	2
LARGE_INTESTINE	DMGDH →	+0.931	+3.321	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 284 associations by consensus.

OR51Q1 by CDH9 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →