CDH8

Across TCGA cell cohorts, CDH8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,080 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CDH8-associated GO terms across cancer lineages are Cytoplasmic translation, Nucleic acid catabolic process, and Regulation of cytoplasmic translation. Each is linked with CDH8 in more than 9 cancer types. Because this analysis shows association rather than direction, both CDH8-to-partner and partner-to-CDH8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by CDH8-low versus CDH8-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH8→partner) and Y-score (partner→CDH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.083	+1.678	.002	<.001	3	10
BONE	Nucleic acid catabolic process →	+0.062	+3.151	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Regulation of cytoplasmic translation →	+0.111	+2.501	.005	.001	3	8
BONE	mRNA transport →	+0.095	+2.860	.001	.001	3	8
BONE	mRNA export from nucleus →	+0.100	+2.838	.001	.001	3	8
BONE	RNA localization →	+0.104	+3.207	.004	.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,080 associations by consensus.

Cytoplasmic translation by CDH8 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →