CDH4

Across TCGA patient cohorts, CDH4 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,639 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDH4-associated proteins across cancer lineages are WDR44, BTK, and DOCK2. Each is linked with CDH4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDH4-to-partner and partner-to-CDH4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDH4 versus WDR44 in GBM, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH4→partner) and Y-score (partner→CDH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WDR44 →	-0.186	-0.977	.004	.005	3	3
GBM	BTK →	-0.367	-0.877	<.001	<.001	3	3
GBM	DOCK2 →	-0.438	-0.966	<.001	<.001	3	3
OV	MCC →	+0.450	+0.327	<.001	<.001	3	3
GBM	NCKAP1L →	-0.493	-1.062	<.001	<.001	3	3
GBM	FYB1 →	-0.520	-1.011	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,639 associations by consensus.

CDH4 vs WDR44 — GBM

Explore this scatter interactively →