CDH4

Across TCGA cell cohorts, CDH4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,247 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDH4-associated GO terms across cancer lineages are Golgi vesicle transport, Negative regulation of binding, and Regulation of post-translational protein modification. Each is linked with CDH4 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDH4-to-partner and partner-to-CDH4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by CDH4-low versus CDH4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH4→partner) and Y-score (partner→CDH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Golgi vesicle transport →	+0.060	+0.278	.001	<.001	3	7
LARGE_INTESTINE	Negative regulation of binding →	+0.097	+0.270	<.001	.001	2	7
STOMACH	Regulation of post-translational protein modification →	+0.061	+0.277	<.001	<.001	2	7
SKIN	Host-mediated activation of viral genome replication →	+0.075	+0.905	<.001	.007	3	6
STOMACH	Regulation of transcription initiation by RNA polymerase II →	+0.061	+0.386	<.001	<.001	3	6
LARGE_INTESTINE	Viral life cycle →	+0.059	+0.185	.004	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,247 associations by consensus.

Golgi vesicle transport by CDH4 expression — STOMACH

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