CDH26

Across TCGA cell cohorts, CDH26 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,396 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDH26-associated GO terms across cancer lineages are Regulation of RNA splicing, Negative regulation of myoblast fusion, and Positive regulation of protein modification by small protein conjugation or removal. Each is linked with CDH26 in more than 8 cancer types. Because this analysis shows association rather than direction, both CDH26-to-partner and partner-to-CDH26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by CDH26-low versus CDH26-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH26→partner) and Y-score (partner→CDH26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of RNA splicing →	+0.079	+0.637	.004	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.096	+0.928	<.001	<.001	3	9
PANCREAS	Positive regulation of protein modification by small protein conjugation or removal →	+0.058	+0.850	<.001	<.001	3	8
STOMACH	Response to starvation →	+0.044	+0.384	<.001	.002	3	8
LUNG_NSCLC_LUAD	Positive regulation of autophagy →	+0.029	+0.426	.008	<.001	3	8
KIDNEY	Pallium development →	+0.056	+0.325	.002	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,396 associations by consensus.

Regulation of RNA splicing by CDH26 expression — OESOPHAGUS

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