CDH26

Across TCGA cell cohorts, CDH26 mutation is significantly associated with the RNA expression of many other genes, with 635 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDH26-associated genes across cancer lineages are CD164L2, ME2, and TMED2. Each is linked with CDH26 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDH26-to-partner and partner-to-CDH26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD164L2 grouped by CDH26-low versus CDH26-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH26→partner) and Y-score (partner→CDH26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CD164L2 →	+0.044	+4.285	<.001	.003	3	2
LARGE_INTESTINE	ME2 →	+1.059	+3.700	<.001	<.001	3	2
LARGE_INTESTINE	TMED2 →	+0.349	+2.459	.009	.006	3	2
BLOOD_Myeloma	SMYD1 →	+0.043	+4.285	<.001	.003	3	1
OESOPHAGUS	GABRA4 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	TXNDC8 →	+0.016	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 635 associations by consensus.

CD164L2 by CDH26 expression — BLOOD_Myeloma

Explore this box plot interactively →