CDH23

Across TCGA patient cohorts, CDH23 protein abundance is significantly associated with the RNA expression of many other genes, with 2,278 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDH23-associated genes across cancer lineages are ABITRAM, IGKV1D-33, and C17orf113. Each is linked with CDH23 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDH23-to-partner and partner-to-CDH23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDH23 versus ABITRAM in LSCC, with a Pearson correlation of -0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH23→partner) and Y-score (partner→CDH23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ABITRAM →	-0.989	-1.565	.002	.002	3	2
LSCC	IGKV1D-33 →	+2.667	+2.107	<.001	<.001	3	2
LSCC	C17orf113 →	-1.189	-1.835	<.001	.004	3	2
UCEC	TSNAXIP1 →	-1.592	-1.798	.006	.002	3	1
UCEC	CA9 →	-2.623	-2.517	.009	<.001	3	1
UCEC	KLHL5 →	+0.891	+2.104	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,278 associations by consensus.

CDH23 vs ABITRAM — LSCC

Explore this scatter interactively →