CDH23

Across TCGA cell cohorts, CDH23 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,259 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CDH23-associated GO terms across cancer lineages are ATP metabolic process, Nucleic acid catabolic process, and Energy derivation by oxidation of organic compounds. Each is linked with CDH23 in more than 10 cancer types. Because this analysis shows association rather than direction, both CDH23-to-partner and partner-to-CDH23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP metabolic process grouped by CDH23-low versus CDH23-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH23→partner) and Y-score (partner→CDH23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	ATP metabolic process →	+0.095	+1.298	<.001	<.001	3	11
BONE	Nucleic acid catabolic process →	+0.058	+2.272	<.001	<.001	3	10
BREAST	Energy derivation by oxidation of organic compounds →	+0.077	+1.317	<.001	<.001	3	10
BONE	RNA catabolic process →	+0.080	+3.243	<.001	<.001	3	10
OVARY	Aerobic electron transport chain →	+0.120	+1.150	<.001	<.001	3	10
OVARY	Cellular respiration →	+0.094	+0.925	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,259 associations by consensus.

ATP metabolic process by CDH23 expression — BREAST

Explore this box plot interactively →