CDH20

Across TCGA patient cohorts, CDH20 mutation is significantly associated with the RNA expression of many other genes, with 4,195 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDH20-associated genes across cancer lineages are HSPD1P18, LINC02724, and CTSG. Each is linked with CDH20 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDH20-to-partner and partner-to-CDH20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSPD1P18 grouped by CDH20-low versus CDH20-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH20→partner) and Y-score (partner→CDH20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	HSPD1P18 →	+0.174	+5.647	<.001	.004	3	4
LUSC	LINC02724 →	-0.220	-3.781	.006	<.001	3	4
LUAD	CTSG →	-0.708	-2.807	.007	.003	3	4
STAD	NARS1 →	+0.624	+2.824	<.001	.001	3	4
LUSC	WDR76 →	+0.615	+2.736	.006	.002	3	4
STAD	CHAC2 →	+0.696	+2.824	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,195 associations by consensus.

HSPD1P18 by CDH20 expression — LIHC

Explore this box plot interactively →