CDH20

Across TCGA pan-cancer cohorts, CDH20 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated CDH20 data layer compared with 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CDH20 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CDH20 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LGG show a favorable association.

HNSC, LGG, and KICH are the cancer types where CDH20 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.770	0.648	<.001	42	view →
LGG	OS	Median	All	0.956	0.834	<.001	40	view →
KICH	OS	Median	III,IV	1.000	0.759	.004	37	view →
THYM	DFS	Median	II,III,IV	0.894	0.581	.001	24	view →
CHOL	DFS	Quartile	II,III,IV	0.796	0.093	.006	24	view →
UVM	DFS	Quartile	All	0.438	0.921	.004	21	view →
BRCA	OS	Tertile	III,IV	0.687	0.509	.021	17	view →
CESC	OS	Median	II,III,IV	0.906	0.746	.011	16	view →
COAD	DFS	Median	All	0.731	0.827	.002	15	view →
LUSC	DFS	Median	All	0.622	0.399	.010	15	view →
ESCA	DFS	Quartile	II,III,IV	0.627	0.294	.016	15	view →
KIRP	DFS	Quartile	IV	0.904	0.546	.024	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

CDH20–HNSC (DFS)

Open the HNSC breakdown →