CDH20

Across TCGA cell cohorts, CDH20 RNA expression is significantly associated with the go_rna of many other GO terms, with 768 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible CDH20-associated GO terms across cancer lineages are Negative regulation of defense response to virus by host, Regulation of retinal ganglion cell axon guidance, and DNA-templated transcription initiation. Each is linked with CDH20 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDH20-to-partner and partner-to-CDH20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of defense response to virus by host grouped by CDH20-low versus CDH20-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH20→partner) and Y-score (partner→CDH20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of defense response to virus by host →	+0.135	+0.084	.003	.005	3	4
LUNG_SCLC	Regulation of retinal ganglion cell axon guidance →	+0.746	+0.778	.003	.005	3	4
STOMACH	DNA-templated transcription initiation →	+0.056	+0.037	<.001	.002	3	4
LIVER	Positive regulation of supramolecular fiber organization →	+0.097	+0.070	<.001	.005	3	3
LIVER	Positive regulation of stress fiber assembly →	+0.106	+0.062	.002	.002	3	3
LIVER	Positive regulation of focal adhesion assembly →	+0.092	+0.057	.008	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 768 associations by consensus.

Negative regulation of defense response to virus by host by CDH20 expression — LIVER

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