CDH19

Across TCGA patient cohorts, CDH19 protein abundance is significantly associated with the RNA expression of many other genes, with 9,564 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDH19-associated genes across cancer lineages are SOX10, PPP1R16B, and KHDRBS2. Each is linked with CDH19 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDH19-to-partner and partner-to-CDH19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDH19 versus SOX10 in GBM, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH19→partner) and Y-score (partner→CDH19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SOX10 →	+2.131	+1.521	<.001	<.001	3	2
GBM	PPP1R16B →	+1.998	+1.375	<.001	.001	3	2
GBM	KHDRBS2 →	+1.085	+1.621	<.001	<.001	3	2
GBM	GABRG2 →	+1.109	+1.421	.009	.008	3	2
GBM	NECAB1 →	+1.573	+1.523	<.001	<.001	3	2
GBM	PLP1 →	+3.906	+1.931	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,564 associations by consensus.

CDH19 vs SOX10 — GBM

Explore this scatter interactively →